
Shop decision
When this relic shows up — buy, hold, or skip.
- Best for
- Best for boards that already fire the keywords on this relic that need a fight-to-fight payoff loop built around Poison.
- Skip when
- Skip when you rarely trigger Poison, or this would be your only piece of that fantasy, or a cheaper enabler would stabilize the board first.
- Shop note
- Legendary engine / identity piece. Prefer it when the board already leans this direction. Stack Poison support around it.
Synergies
Relics that share combat tags with this one — useful pairing candidates.

Poison Ascendancy
Inflict 400 Poison. The first time each enemy reaches 50 Poison, they lose 33% Max HP, 66% Attack, and 66% Attack Speed.

Assassin's Ambush Engine
Heroes gain 30 Crit. Whenever an Assassin auto attacks while Stealthed, they inflict Poison on their target equal to 30% of their Crit. At start of combat, Assassins in the back 1 rows gain Stealth for 1 seconds and target the most threatening enemy.

Assassin's Emblem
If there is an Assassin in combat, Heroes gain Stealth for 1 seconds the first time they go below 3% Max HP each combat.

Assassin's Smokescreen Banner
Assassins gain Stealth for 1 seconds the first time they go below 100% Max HP each combat.

Blight Resonance Prism
Whenever an enemy takes Poison or Burn damage, heal all adjacent Heroes to them for 100% of that damage.

Burn Vessel
Inflict 300 Burn. Heroes gain 200 Max HP and 25 Attack.