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Poison Ascendancy

Poison Ascendancy

Epic

Inflict 400 Poison. The first time each enemy reaches 50 Poison, they lose 33% Max HP, 66% Attack, and 66% Attack Speed.

Shop decision

When this relic shows up — buy, hold, or skip.

Best for
Best as a late luxury when built around Poison and you can afford a high-rarity slot.
Skip when
Skip when you rarely trigger Poison.
Shop note
Epic late luxury. Prefer it when the board already leans this direction. Stack Poison support around it.