Shop decision
When this relic shows up — buy, hold, or skip.
- Best for
- Best as a power spike on boards that already fire the keywords on this relic once the core loop is online.
- Skip when
- Skip when you rarely trigger Poison, Burn, and Heal.
- Shop note
- Epic mid–late power spike. Prefer it when the board already leans this direction. Stack Poison, Burn, and Heal support around it.
Synergies
Relics that share combat tags with this one — useful pairing candidates.
Duelist's Rhythm Prism
Whenever a Duelist auto attacks, they randomly inflict 1 Poison, 0 Frost, or 0 Burn on their target.
Plague Ascendancy
Inflict 25 Poison, 50 Frost, and 75 Burn on a single enemy. At start of Combat, inflict 75 Poison, 50 Frost, and 25 Burn on all enemies.
Plague Bauble
At start of combat, inflict 3 Poison, inflict 6 Frost, inflict 9 Burn on enemies
Plague Generator
At start of combat, inflict 1 Poison, 1 Frost, and 1 Burn on all enemies.
Plague Transmission Engine
At start of combat and every 1 seconds, inflict 1 Poison, 1 Frost, and 10 Burn on all enemies.
Assassin's Ambush Engine
Heroes gain 30 Crit. Whenever an Assassin auto attacks while Stealthed, they inflict Poison on their target equal to 30% of their Crit. At start of combat, Assassins in the back 1 rows gain Stealth for 1 seconds and target the most threatening enemy.