
Shop decision
When this relic shows up — buy, hold, or skip.
- Best for
- Best for boards that already fire the keywords on this relic built around Poison.
- Skip when
- Skip when you rarely trigger Poison, or a cheaper enabler would stabilize the board first.
- Shop note
- Unique late luxury. Prefer it when the board already leans this direction. Stack Poison support around it.
Synergies
Relics that share combat tags with this one — useful pairing candidates.

Assassin's Ambush Engine
Heroes gain 30 Crit. Whenever an Assassin auto attacks while Stealthed, they inflict Poison on their target equal to 30% of their Crit. At start of combat, Assassins in the back 1 rows gain Stealth for 1 seconds and target the most threatening enemy.

Blight Resonance Prism
Whenever an enemy takes Poison or Burn damage, heal all adjacent Heroes to them for 100% of that damage.

Deceleration Corruptor
After Stall (0) and Stall (1), double the amount of Poison on all enemies.

Duelist's Rhythm Prism
Whenever a Duelist auto attacks, they randomly inflict 1 Poison, 0 Frost, or 0 Burn on their target.

Duelist's Toxin Banner
Whenever a Duelist auto attacks, they inflict 1 Poison on their target.

Plague Ascendancy
Inflict 25 Poison, 50 Frost, and 75 Burn on a single enemy. At start of Combat, inflict 75 Poison, 50 Frost, and 25 Burn on all enemies.